BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE
beta,beta,beta-trichloro-tert-butyl chloroformate
CAS: 66270-36-8
Molecular Formula: C5H6Cl4O2
BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE - Names and Identifiers
BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE - Physico-chemical Properties
| Molecular Formula | C5H6Cl4O2 |
| Molar Mass | 239.91 |
| Density | 1.4953 (estimate) |
| Melting Point | 28-30°C(lit.) |
| Boling Point | 83-84°C14mm Hg(lit.) |
| Flash Point | 86.1°C |
| Solubility | ethanol: soluble10%, clear, colorless |
| Vapor Presure | 0.407mmHg at 25°C |
| BRN | 1935464 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.49 |
BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2928 6.1/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 4.5-10-19-21 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE - Introduction
Beta, beta,beta-trichloro-tert-butyl chloroformate, also known as beta,beta,beta-trichloro-tert-butyl chloroformate, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: beta,beta,beta-trichloro-tert-butyl chloroformate is a colorless liquid.
-Boiling point: The boiling point of the compound is 113-116 degrees Celsius.
-Density: beta,beta, the density of beta-trichloro-tert-butyl chloroformate is 1.328 g/ml.
-Solubility: The compound can be dissolved in many organic solvents, such as ethanol, methanol and ether.
Use:
- beta,beta,beta-trichloro-tert-butyl chloroformate are commonly used in organic synthesis as acyl chloride reagents. It can be reacted with an alcohol, amine or other nucleophile to form the corresponding ester, amide or imine compound.
-This compound can also be used to prepare protecting groups for ester compounds to prevent other reactions.
Preparation Method:
- beta,beta,beta-trichloro-tert-butyl chloroformate are usually prepared by reacting chloroformic acid trichloride and trans-butyl chloromethanol. The reaction needs to be carried out under an inert atmosphere, such as a nitrogen atmosphere.
Safety Information:
- beta,beta,beta-trichloro-tert-butyl chloroformate should avoid contact with strong oxidants and strong bases, as it may react violently.
-When using, wear appropriate protective gloves and glasses to avoid direct contact with skin and eyes.
-The compound may be irritating and sensitizing to the human body and should be used with caution.
-When using or storing, the regulations and safe operation guidelines for chemicals should be observed.
Nature:
-Appearance: beta,beta,beta-trichloro-tert-butyl chloroformate is a colorless liquid.
-Boiling point: The boiling point of the compound is 113-116 degrees Celsius.
-Density: beta,beta, the density of beta-trichloro-tert-butyl chloroformate is 1.328 g/ml.
-Solubility: The compound can be dissolved in many organic solvents, such as ethanol, methanol and ether.
Use:
- beta,beta,beta-trichloro-tert-butyl chloroformate are commonly used in organic synthesis as acyl chloride reagents. It can be reacted with an alcohol, amine or other nucleophile to form the corresponding ester, amide or imine compound.
-This compound can also be used to prepare protecting groups for ester compounds to prevent other reactions.
Preparation Method:
- beta,beta,beta-trichloro-tert-butyl chloroformate are usually prepared by reacting chloroformic acid trichloride and trans-butyl chloromethanol. The reaction needs to be carried out under an inert atmosphere, such as a nitrogen atmosphere.
Safety Information:
- beta,beta,beta-trichloro-tert-butyl chloroformate should avoid contact with strong oxidants and strong bases, as it may react violently.
-When using, wear appropriate protective gloves and glasses to avoid direct contact with skin and eyes.
-The compound may be irritating and sensitizing to the human body and should be used with caution.
-When using or storing, the regulations and safe operation guidelines for chemicals should be observed.
Last Update：2024-04-09 02:00:47
